Port 443 is the default port for HTTPS, meaning HTTP carried inside a TLS protected channel.
A port is a transport layer number used together with an IP address and a protocol such as TCP or UDP to direct traffic to the correct service on a host.
A server process binds a socket to a port and listens, while a client typically chooses an ephemeral source port for outbound connections.
The combination of source and destination IP addresses, source and destination ports, and the transport protocol uniquely identifies a flow so the operating system can keep many conversations separate.
Firewalls, NAT, and scanners talk about ports because the destination port is the stable rendezvous point that exposes a service to the network.
In the common TCP based case, the client opens a TCP connection to destination port 443, performs the TCP handshake, then performs a TLS handshake where the server proves its identity with a certificate and both sides derive encryption keys.
Only then do HTTP requests and responses flow inside the encrypted tunnel, often with connection reuse for many requests.
Modern web stacks also use HTTP over QUIC, known as HTTP/3, which runs over UDP on port 443.
That is why you may see both TCP 443 and UDP 443 involved in web traffic.
Port 443 matters because it is the most common externally reachable service on the internet, so it is both a business critical entry point and a favorite hiding place for tunneling and command and control.
Encryption protects transport confidentiality, but application vulnerabilities, weak authentication, and misconfiguration are still the real risks on 443.